Pancreatogastrostomy Versus Pancreatojejunostomy for RECOnstruction After PANCreatoduodenectomy (RECOPANC, DRKS 00000767): Perioperative and Long-term Results of a Multicenter Randomized Controlled Trial.

Tobias Keck, U. F. Wellner, M. Bahra, F. Klein, O. Sick, M. Niedergethmann, T. J. Wilhelm, S. A. Farkas, T. Börner, C. Bruns, A. Kleespies, J. Kleeff, A. L. Mihaljevic, W. Uhl, MD,yy A. Chromik, V. Fendrich, K. Heeger, W. Padberg, A. Hecker, U. P. Neumann, K. Junge, J. C. Kalff, T. R. Glowka, J. Werner, MD, P. Knebel, P. Piso, M. Mayr, J. Izbicki, Y. Vashist, P. Bronsert, T. Bruckner, R. Limprecht, M. K. Diener, I. Rossion, I. Wegener, and U. T. Hopt.
Ann Surg . 2016 Mar;263(3):440-9.

• 440 patients were randomized, 320 included in the intention-to-treat analysis. 
• No significant difference in the rate of grade B/C fistula after PG = 20% versus PJ = 22% (P = 0.617). 
• The overall incidence of grade B/C fistula = 21%, 
• In-hospital mortality = 6%. 
• Multivariate analysis POPF : soft pancreatic texture (P = 0.016) was the only independent risk factor. 
• Compared with PJ, PG was associated with an increased rate of
  • Grade A/B bleeding events,
  • Perioperative stroke,
  • Less enzyme supplementation at 6 months,
  • Improved results in some quality of life parameters.